Saturday, August 9, 2008

Remembering the Anthrax Vaccine Controversy

Crossposted from our new home blog,They gave us a republic...


I remember the controvery over having to receive shots of the Anthrax vaccine--no one knew if it was causing serious health problems and members of the military were refusing to get the shots:

Military personnel, under the threat of court-martial, were refusing inoculations of an anthrax vaccine. The vaccine’s sole manufacturing plant was ordered to shut down. Researchers were turning up evidence possibly linking the vaccine to illnesses of soldiers during the Persian Gulf war of 1991.

It was hardly the thank you that Dr. Bruce E. Ivins expected for his years of labor to produce a vaccine that would protect military personnel from an anthrax attack by the Iraqi leader Saddam Hussein or some other adversary.

The criticism, which reached its peak in 2000 and early 2001, was clearly starting to get on Dr. Ivins’s nerves. “I think the **** is about to hit the fan ... big time,” he wrote in a July 2000 e-mail message about the inoculation program, according to a government affidavit. “It’s just a fine mess.”

This turmoil has now been cited by federal investigators as a key part of the reason they believe that Dr. Ivins sent out anthrax-laced letters in the fall of 2001 — as such an attack would, in a single stroke, have eliminated the skepticism and second guessing about the need for an anthrax vaccine.


They ran out before I was supposed to receive the shots--a series of several painful shots over an extended period of time--and I never got it. My wife received the shots, and told me she experienced a great deal of pain in her arm.


But it is true--there was turmoil. A handful of people were refusing to get it, touching off controversy. Well, not controversy. Mostly, disgust that there were people refusing to follow orders.

This was a fight the military wasn't going to lose, of course, and many were forced to get the shots (until they ran out, of course).

I don't know why they're continuing to use all of these different issues to pound Dr. Bruce Ivins, but this is essentially what was going on:

This turmoil has now been cited by federal investigators as a key part of the reason they believe that Dr. Ivins sent out anthrax-laced letters in the fall of 2001 — as such an attack would, in a single stroke, have eliminated the skepticism and second guessing about the need for an anthrax vaccine.

The investigators suggest that Dr. Ivins had been struggling with psychological problems, and was on medication and undergoing counseling after being overcome by what he described as paranoid, delusional thoughts. The trouble with the vaccine, they argue, may have been enough to set him off.


At that stage of his career, was he ready to risk everything and do something that just seems stupid--and that is, use weaponized Anthrax to prove what he was working on was vital and necessary? You have to assume he was willing to take steps that are unimaginable for someone working on a way to keep people safe from being killed by Anthrax. You have to be willing to suspend a lot of disbelief for that theory to work.

Dr. Ivins’s former colleagues reject that two-part theory, saying it is just one of many flaws in the evidence presented by the government in an unconvincing case.

There was a real threat, the former colleagues acknowledged, that the anthrax vaccine Dr. Ivins had worked on during that period, known as Anthrax Vaccine Absorbed or AVA, might be pulled from the market

Most troubling were problems at the Michigan manufacturing plant, which had been shut down in 1998 after the Food and Drug Administration uncovered serious flaws.

Dr. Ivins and other researchers, however, had been working on a more advanced alternative vaccine — considered safer and more effective — so there was no reason for such a rash act, his former colleagues say.

“There was a lot of consternation, a lot of pressure to rescue this thing,” said Jeffrey Adamovicz, one of Dr. Ivins’s fellow researchers at the time. “But if AVA failed, he had his next vaccine candidate. It was well on its way to what looked to be a very bright future.”

The vaccine controversy erupted in the late 1990s, after the Defense Department ordered the inoculation of all 2.4 million active duty and reserve troops, starting with those most likely to confront biological attacks in war zones, partly because Iraq had confirmed that it once had a large stockpile of anthrax that was destroyed after the first Persian Gulf war.

By 2000, more than 570,000 military personnel had complied with the order, and hundreds had filed an “adverse event report” after receiving the shots, citing reactions that included fatigue, dizziness and muscle pain, and more serious conditions like thyroid disorders and rhabdomyolysis, a muscle ailment.


It was scary, but there was nothing you could do about it. Once you join the military, be prepared to follow every stupid order. That's just how it is.

What the Justice Department has not produced is evidence documenting that Dr. Ivins’s frustrations motivated him to retaliate with the anthrax letters.

Gerard P. Andrews, another of Dr. Ivins’s former colleagues, said he knew that Dr. Ivins was frustrated, but that he doubted that Dr. Ivins would consider such a step.


Well, we lived with the controversy, and I've never regretted the fact that they ran out of the vaccine before I had to get it.
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Russian Jets Pound Targets in Georgia

Crossposted from our new home blog,They gave us a republic...


The violence in the region is escalating...

Russian jets have carried out strikes on military targets in the central Georgian town of Gori, close to the breakaway region of South Ossetia.

Most of the targets seem to have been military bases, but Georgian officials said a number of civilians had been killed in residential buildings.

Russia said it had "liberated" the South Ossetian capital, Tskhinvali.

Earlier, Russian President Dmitry Medvedev said his country was seeking "to force the Georgian side to peace".

The comments came after Russian commanders announced they were sending more troops into South Ossetia to support peacekeeping operations.

The Russian defence ministry confirmed two of its jets had been shot down over Georgia, although it did not say where.

In a live televised address, Georgian President Mikhail Saakashvili said he would ask parliament to approve the introduction of martial law.

After days of exchanging heavy fire with the Russian-backed separatists, Georgian forces launched a surprise attack on Thursday night to regain control of the region, which has had de facto independence since a war in 1992.



Georgian troops in the city of Gori (NY Times)

A small contingent of US troops is in Georgia, and since Russian forces are attacking Georgian military installations, it is not known if they are in imminent danger:

About 130 U.S. military and civilian personnel are currently located in Georgia, where they are training Georgian troops for deployment to Iraq as part of the multinational force there. U.S. military officials in Baghdad said they had gotten no official word about statements from Tblisi that half of Georgia's 2,000-troop contingent was being called home.



It isn't something that is front and center in the reporting, since attacks on civilians are the real story here. But when you start to think about why the sides are fighting, it really does come down to energy revenues:

The BBC's Richard Galpin in Gori heard loud explosions and saw large plumes of smoke rising into the sky; soldiers and civilians were seen running through the streets.

One missile hit a military base, from which most of the soldiers appeared to have managed to escape beforehand, he says.

The Georgian military said residential buildings had also been struck, leaving a number of civilians dead. Our correspondent says injured civilians were being pulled from the buildings, which were on fire.

The Georgian foreign ministry said the Black Sea port of Poti, which is the site of a major oil shipment facility, had also been "devastated" by a Russian aerial bombardment.



Georgian troops riding to the front (NY Times)

The US and the United Nations seem ineffectual, unable to get past the Russian veto on the Security Council:

International Red Cross (ICRC) spokeswoman Anna Nelson said the ICRC had received reports that hospitals in the city were "overflowing" with casualties.

The BBC's James Rodgers in Moscow says diplomatic initiatives to end the fighting have so far proved fruitless.

On Friday evening, the UN Security Council failed to agree on the wording of a statement calling for a ceasefire.

Russia holds a permanent place on the Council, and has the power of veto over any official statements that it regards as unfair or inaccurate.

Permanent members Britain, the US and France, are pinpointing what they say is Russia's aggression as the key factor in the slide towards war, while Moscow insists Georgia is to blame.

In other developments:

US Secretary of State Condoleezza Rice called on Russia to pull its troops out of Georgia and respect its territorial integrity
Georgia's president said his country was withdrawing its contingent of 2,000 troops from Iraq to help deal with the crisis
The European security organisation, the OSCE, warned that the fighting in South Ossetia could escalate into a full-scale war
The US and the EU were reported to be sending a joint delegation to the region to seek a ceasefire and Nato said it was seriously concerned.


She needs to go to Moscow and/or the region immediately. Not some envoy, not some flunky--she's the expert on Russia, and her area of expertise has so far proven to be an area of foreign policy in which she's about as effective as everywhere else she tries her hand--and that's not very damned much.

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